Technician CLD

Basel

Full-time

Permanent employee

The Position

The Technician CLD supports the development of processes and/or the analysis for the manufacturing of recombinant proteins with CHO cultures by executing experiments, preparing materials, and collecting data.

Your Responsibilities

Conduct experiments and apply standard laboratory practices under moderate guidance and supervision within scope and timelines
Document executed work in accordance to internal guidelines
Support troubleshooting activities in collaboration with Subject Matter Expert
Document batch results with a critical mind
Write protocols, SOPs, using available templates
Drive simple initiatives (in relation to job duties) with limited guidance and supervision within your team/group
Support technology transfer activities if needed
Follow all EHS procedures and laboratory safety standards, maintain a clean and safe workspace, and promptly report any unsafe conditions, incidents, or near misses

Job Requirements

Cell Line Development (CLD) technical skills:

Gene synthesis, vector cloning, plasmid purification, sequencing, agarose gel electrophoresis
Plasmid design software (e.g., vector mapping and annotation tools)
Transfection techniques and clone selection workflows; Clonality assessment (e.g. FACSAria, FACSLyric, Single cell printing (VIPS), Cellmetric)
Expansion and cryopreservation of cell lines
Small-scale bioreactor systems used in early screening (e.g., Ambr15, Breez)
E.coli culture, CHO cell suspension culture

Other desirable technical skills: Cell culture expansion in shake flasks, wave bags, and benchtop bioreactors, use of single-use bioreactors at laboratory and pilot scale, Monitoring and control of critical culture parameters (e.g., pH, DO, temperature, agitation, feeding), Routine sampling for cell growth and metabolic profiling, Basic troubleshooting and maintenance of bioreactor and support systems

Excellent communication skills (English required, German is a plus)
Solution-oriented mindset
Ability to work in a fast paced environment
Collaborative team player
Ability to deal with changes and quickly adjust to new situations

Why Celonic?

Make a difference by directly impacting patients lives
Biologics is an attractive, high growth sector with professional development
Offers a multinational and diverse workplace
Proud to be a pioneer in “Next Generation” manufacturing technologies
Family owned: Entrepreneurial, and short communication lines
Basel is a great place to live, play and work in the center of Europe

Über uns

Celonic ist eine „Pure Play“ Biologics Contract Development Manufacturing Organization (CDMO). Celonic hat es sich zur Aufgabe gemacht, ihre Kunden, in erster Linie kleine bis große Biotech-Unternehmen, dabei zu unterstützen, lebensrettende und -verbessernde Medikamente unter Einsatz innovativer Bioprozesstechnologien der nächsten Generation effektiv auf den Markt zu bringen. Celonic verfügt über ein hochmodernes Entwicklungs- und Innovationszentrum in Basel, Schweiz (Hauptsitz), sowie über klinische und kommerzielle GMP-Produktionsanlagen in Heidelberg, Deutschland. Gegenwärtig arbeiten mehr als 500 hochqualifizierte Mitarbeiter bei Celonic. Aufgrund der Expansion des Unternehmens ist Celonic auf der Suche nach engagierten und qualifizierten Mitarbeitern.

Our job is to make a difference!

http://www.celonic.com/